M. Shahwan

Network Biology of Alzheimer’s Disease and Related Neurodegenerative Disorders: Molecular Mechanisms and Therapeutic Strategies

This study redefines neurodegeneration as a disorder of system-level failure by emphasizing poor cellular stress integration and explores progress in fluid, digital, and imaging biomarkers that facilitate early diagnosis and patient stratification, and assesses new disease-modifying approaches such as antisense oligonucleotides, immunomodulators, gene therapies, and small-molecular agents.