Open access
Oct 2026
Background: Cognitive impairment in Parkinson disease (PD) significantly affects patients ability to perform instrumental activities of daily living (IADLs). However, neuropsychiatric symptoms, which are highly prevalent in PD, may also contribute to functional impairments. In this study, we investigated the independen...
J.-Y. Hu, S. Sun, M. Sharp
· medRxiv · 0 citations
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Open access
Jul 2026
It is suggested that in early-stage PD, nbM microstructural changes may account for unique variance in executive dysfunction in PD, independent of the effects of LC degeneration, and with a stronger association in PD than controls.
A. Bailey, E. St-Onge, V. Madge et al.
· medRxiv · 0 citations
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Open access
Jul 2026
The results suggest that co-morbid AD pathology is not a major contributor to early cognitive changes in this sample of PD patients without dementia.
T. Kouchache, T. Chan, Sophie Sun et al.
· Movement Disorders · 1 citation
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