Author

M. Siddiqui

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Open access Oct 2026

Withania somnifera triggers cytotoxicity and apoptosis in cancer cells through mitochondrial dysfunction and oxidative stress

Cancer remains one of the top deadly diseases, largely due to lack of definitive and effective therapeutic agent. Withania somnifera, a renowned remedy, widely been used in ancient medication to help with several diseases. This study aims to investigate the potential anticancer effect in HepG2, MCF-7 and A-549 cell...

E. S. Al-Sheddi, M. Al-Oqail, N. Farshori et al. · Journal of King Saud Univers... · 0 citations

Open access Sep 2026

GC-MS Profiling, Phenolic and Flavonoid Contents, Exploratory Cytotoxicity in MCF-7 Cells and Surrogate Anthelmintic Screening of Zygophyllum propinquum Methanolic Extract

Background: Medicinal plants are important sources of structurally diverse secondary metabolites with potential biological activities. Zygophyllum propinquum is a halophytic medicinal plant whose phytochemical composition and biological properties remain insufficiently characterized. This study investigated the phytoch...

S. Maodaa, E. Al-Shaebi, A. Ghfar et al. · Indian Journal of Animal Res... · 0 citations

Open access Oct 2026

Rotenone-Induced Cytotoxicity in Human Umbilical Vein Endothelial Cells (HUVECs): Involvement of Oxidative Stress, Mitochondrial Dysfunction, and Intrinsic Apoptosis.

Rotenone is a well-defined inhibitor of Mitochondrial Complex I, which induces oxidative stress and apoptosis in various cell types. However, its cytotoxicity and molecular mechanisms in human umbilical vein endothelial cells (HUVECs) remain unexplored. Therefore, the purpose of this study was to examine the effects of...

M. Siddiqui, N. Farshori · Journal of Applied Toxicolog... · 0 citations