Human epidermal growth factor receptor 2-directed therapeutics and their role in changing the natural course of breast cancer.
ErbB/EGFR (erythroblastosis B/epidermal growth factor receptor) family members play a role in driving the growth of various solid tumours. Therapeutic agents directed against two receptor family members, EGFR and human epidermal growth factor receptor 2 (HER2/ErbB2), show meaningful clinical benefit in solid tumours, i...