M. Thevis

Simultaneous Detection of Steroid Esters and Multi-Class Substances in Dried Blood Spots by LC-HRMS/MS From a Single Spot for Human Doping Control.

The direct detection of intact anabolic steroid esters in blood constitutes unequivocal evidence of exogenous administration and therefore represents a valuable target for anti-doping testing. Dried blood spots (DBSs) offer several practical advantages over conventional blood sampling and may improve the stability of s...

Urinary detection and metabolites profiles of trenbolone and metenolone following trace-level dermal exposure.

Strengthening the interpretation of longitudinal EQA data through the sporadic inclusion of native human sera in general clinical chemistry

Comparative external quality assessment (EQA) surveys using native human sera alongside routinely distributed processed EQA materials (EQAMs) provide valuable information on measurement procedure (MP) trueness and the status of standardization. They also allow EQA providers to retrospectively identify critical or l...

Quantification of the Carboxylated LGD‐4033 Long‐Term Metabolite in Human Micro‐Dose Excretion Study Urine Samples

The quantitative data generated in this study provide an important basis for improved interpretation of adverse analytical findings involving LGD‐4033 and support a more evidence‐based distinction between different intake scenarios.

Investigation Into the Metabolism and Elimination Behavior of RU 58841, and Its Influence on the Steroid Profile in Humans

It is indicated that a single topical dose of 30 mg does not interfere with SP parameter determinations in routine doping controls, and the metabolism and the systemic exposure of RU 58841 are assessed.