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Open access Sep 2026

Genetic background shapes the naïve IgM B cell receptor repertoire in mice

Introduction The B cell receptor (BCR) repertoire is generated through stochastic V(D)J recombination and further shaped by selection processes. Still, the influence of genetic background on the naïve repertoire remains unclear. In this study, we investigated inter-individual and inter-strain variations in the IgM BCR...

Hina Wakimizu, M. Tsuiji, Chiaki Nishihara et al. · 0 citations

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