M. van Weeghel

Mitochondrial carrier SLC25A34 links clock, diet, and temperature control of adipocyte lipid cycling.

Adipocyte lipid metabolism is coordinated by circadian rhythms, diet, and environmental temperature, but how these diverse signals are molecularly integrated remains unknown. We showed that these cues converge on the orphan mitochondrial transporter SLC25A34 to orchestrate lipid cycling. During the sleep phase, the adi...

Metabolic benefits of ketohexokinase inhibition in individuals with MASLD: a randomized placebo-controlled crossover trial.

Characterization of the metabolome and proteome of stem cell-derived human primordial germ cell-like cells: a multi-omics approach

An integrative map of these metabolic networks is provided to provide insight into the metabolism of hPGCLC development that could help improve methods for fully in vitro differentiation and maturation of hPGCLCs.