Author

M. Varkolu

3 papers indexed here

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Open access Sep 2026

Eco‐Friendly LC–MS/MS Determination of N ‐Nitroso Vildagliptin Amide, a Nitrosamine Carcinogenic Impurity, in Vildagliptin Drug Substance Using Advanced Greenness Metrics

In the process of making vildagliptin (VG) API, one of the nitrosamine groups found in the drug is N ‐nitroso vildagliptin amide (NVA). This led to the development of a multi‐reaction monitoring (MRM) approach that is both sensitive and reliable for quantitatively assessing NVA impurity in VG API. Using isocratic...

Raj Kumar Kodishala, Kousrali Sayyad, Pravardhan Reddy Elala et al. · Separation Science Plus · 0 citations

Review Open access Oct 2026

A concise review of mechanochemistry as a greener tool in sustainable synthesis of heterocyclic moieties

The growing environmental and economic concerns surrounding traditional chemical synthesis have accelerated the demand for sustainable, greener methodologies. Green chemistry offers a framework for designing processes that minimize hazardous waste, reduce energy consumption, and use safer reagents. Among various emergi...

H. K. Edapu, R. Pagadala, M. Varkolu et al. · Arabian Journal of Chemistry · 0 citations

Review Aug 2026

Recent highlights in extraction of pigments from plant and algae resources using supercritical fluids

Growing environmental concerns associated with fossil‐based materials, coupled with their limited reserves, have intensified the global pursuit of renewable alternatives. Among these, natural pigments derived from plants and algae are emerging as promising sustainable resources with diverse industrial applications....

Sai Pallavi Thurlapati, Sreedhar Gundekari, Ambika Manupathi et al. · Canadian Journal of Chemical... · 0 citations