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Author

M. Vaškovičová

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2 papers indexed here

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Open access Oct 2026

TEAD4 Regulates apical domain homeostasis and cell-positioning to maintain the trophectoderm lineage during mouse blastocyst development

Abstract In mammalian preimplantation embryos, distinct cell lineages occupy defined spatial niches. The outer trophectoderm (TE) forms an epithelial monolayer surrounding the inner cell mass (ICM) and blastocyst cavity. In mice, the Tead4 gene encodes a polarity-dependent transcription factor required for TE specifica...

Rebecca Collier, Martina Bohuslavová, M. Vaškovičová et al. · 0 citations
Open access Sep 2026

Activating a patient-relevant pathogenic variant of a genetically defined heart disease in a humanized pig model

The study describes the generation of a humanized pig model carrying an inducible phospholamban R14del mutation for cardiomyopathy modeling and demonstrates Cre-based activation strategies as efficient alternatives to germline Cre-driver lines in large animals.

Petra Runa-Vochozkova, M. Vaškovičová, J. Cambra et al. · 0 citations

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