Confounder-Adjusted Plasma Proteomics Identify Robust Protein Signatures in Sepsis Across Two Independent Perioperative Control Cohorts
Background Sepsis is the primary driver of mortality in intensive care. Personalized medicine requires an accurate understanding of the syndrome, and plasma proteomics is increasingly used to characterize its molecular alterations. Comorbidities, demographics and postoperative sterile inflammation complicate this task,...