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Reduced Paramagnetic Rim Visibility Signals Lesion Aging and Tissue Degeneration in Progressive Multiple Sclerosis
Underlying tissue destruction in Definite vs Probable PRLs in people with progressive MS is assessed using quantitative MRI to assess underlying tissue destruction in PRLs in people with progressive MS.
Immune Profiling after treatment with an Anti-CD19 Chimeric Antigen Receptor T Cell Therapy in Treatment-Refractory Progressive Multiple Sclerosis
Low dose anti CD19 CAR T cell therapy was safe, penetrated the CSF effectively, reduced intrathecal humoral activity, modulated peripheral immune tone, and appeared to stabilize EDSS scores, which support the continued investigation of CAR T cell therapy in MS.