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Open access Sep 2026

851. A mechanism for PHF21B recognition of H3K36me3

Abstract Background We have recently identified the epigenetic reader PHF21B as a regulator of synaptic plasticity and social memory in mice. The PHF21B gene is located on chromosome 22q13.3, a region that is deleted in Phelan-McDermid syndrome, a neurodevelopmental disorder characterized by intellectual disability, im...

M. Wong, Q. Ma, J. Licinio · 0 citations

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