Author

M. Y. Rincon

2 papers indexed here

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Review Open access Sep 2026

Global seroprevalence of neutralizing and total antibodies against AAV vectors and their impact on the clinical gene therapy landscape: a scoping review

A scoping review of 50 studies published between 1968 and 2026 found AAV2, AAV8, and AAV5 were the most extensively studied serotypes and seroprevalence increased consistently with age and varied by geographic region, although the limited number of studies from Africa and Latin America precludes robust regional conclus...

Cristina Sánchez Gutierrez, Luisa Fernanda Bohorquez-Zambrano, Camila Garnica-Álvarez et al. · Frontiers in Medicine · 0 citations

Review Oct 2026

Reframing liver test abnormalities after AAV gene therapy: a mechanistic diagnostic framework.

Hepatotoxicity remains one of the most frequent and clinically important safety concerns in adeno-associated virus (AAV) gene therapy. Yet the laboratory patterns observed after vector administration are biologically complex and often difficult to interpret. Alanine aminotransferase (ALT) and aspartate aminotransferase...

B. Henry, B. Bénichou, M. Y. Rincon et al. · Clinical Biochemistry · 0 citations