Osteochondral defects remain a major clinical challenge, frequently progressing to osteoarthritis and ultimately requiring joint replacement. Despite advances in regenerative strategies, current approaches often fail to restore the structural and functional complexity of the osteochondral unit, resulting in poor integr...
P. Fisch, I. Roohani, S. Ponta et al.· bioRxiv· 0 citations
A persistent challenge in cartilage tissue engineering is identifying cell sources capable of regenerating cartilage with native-like properties. Variability in chondrogenic potential among human- and animal-derived cells complicates graft development and disease modeling. Here we benchmarked ten chondrogenic cell sour...
S. Ponta, Valerie Pecina, Marielle Airoldi et al.· bioRxiv· 0 citations
Biofabrication is a multidisciplinary field that integrates diverse technologies to create three-dimensional structures composed of living cells, biomaterials, and other biological components. One of its main goals is the realization of functional tissue constructs with hierarchical architectures, as observed in native...
O. Kopinski-Grünwald, Corinna Barella, A. Budaeva et al.· Biofabrication· 0 citations
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