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Author

M. Zihlif

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Open access Sep 2026

Genetic factors associated with COVID-19 severity and mortality: TYK2 and NOTCH4.

The clinical manifestations and outcomes of coronavirus disease (COVID-19) vary among patients. Emerging evidence indicates that host genetic factors may influence disease severity. Genome-wide association studies (GWAS) have identified several genetic loci, including TYK2 and NOTCH4, as contributors to COVID-19 pathog...

M. Al-Rshaidat, A. Alsayed, Omar Al-Rshaidat et al. · 0 citations
Open access Aug 2026

In silico discovery of RIOK3 inhibitors against pancreatic ductal adenocarcinoma using homology modelling, molecular docking, molecular dynamics simulations, ADMET prediction, and MTT assay

RIOK3 is identified as a promising therapeutic target for PDAC, with Venetoclax, Conivaptan, Drospirenone, and Irinotecan as repurposable candidates for further research.

Kawthar Alhussieni, R. Othman, Tamilanban Thamaraikani et al. · 1 citation
Open access Aug 2026

Association of HTR2A (rs6313) gene polymorphism with autism spectrum disorder in Jordanian children: a case-control study

The findings suggest no significant association between the HTR2A rs6313 and ASD susceptibility in the Jordanian population, and emphasize the need for larger, multi-marker studies to account for regional genetic diversity.

Wiam Khalil, Elaf Adel Al-Dalabeeh, M. Zihlif · 0 citations
Jul 2026

Lack of Association between the Cytochrome P450 4F2 rs2108622 Genotype and Responses to Valsartan and Amlodipine among a Sample of Jordanian Hypertensive Patients.

There is a lack of association between the CYP4F2 rs2108622 genotype and valsartan and amlodipine responses among a sample of Jordanians with essential hypertension, and the absence of statistical significance supports the need for larger pharmacogenetic studies.

Y. Jarrar, Enas Yousef Alkasasbeh, Dalia Abdelrazaq et al. · 0 citations

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