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Open access Oct 2026

Vancomycin Population Pharmacokinetics and Exposure Variability in Children with Multiple Organ Dysfunction Syndrome.

In children with multiple organ dysfunction syndrome (MODS), vancomycin dosing is frequently guided by population-based approaches followed by therapeutic drug monitoring that requires considerable blood volumes. We sought to develop a population pharmacokinetic (PK) model and describe vancomycin exposures using blood-...

Marc H. Scheetz, Justin Shiau, Victor Amajor et al. · 0 citations
Open access Oct 2026

Biallelic loss-of-function PTPN6 variants lead to inflammatory lung disease and hemolytic anemia

Moussavi-Harami et al. report that biallelic loss-of-function variants in PTPN6, encoding the immune-regulatory phosphatase SHP1, cause anemia and fatal lung hyperinflammation in families from diverse ethnic backgrounds.

S. Moussavi-Harami, M. Zinter, M. Motta et al. · 0 citations

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