Review
Open access
Aug 2026
Estetrol and its implications for contraception, venous thromboembolism, and breast cancer: an integrative review
Abstract Combined oral contraceptives (COCs) provide benefits beyond contraception but are associated with risks such as venous thromboembolism (VTE) and breast cancer. This integrative review aimed to evaluate the efficacy and safety of estetrol (E4)-containing COCs regarding their risk of VTE and breast cancer. The P...
Marcos Arêas Marques, Suzanna Maria Viana Sanches, Monique Magnavita Borba da Fonseca Cerqueira et al.
· Jornal Vascular Brasileiro · 0 citations