Madalyn Heaton-Ward

Animal versus human oral drug bioavailability: machine learning says yes – they correlate

Oral bioavailability (%F) is a key determinant of drug efficacy and a critical decision-making parameter in early-stage drug development. Current prediction of human oral %F often relies on preclinical animal studies, which are costly, ethically disputed and do not necessarily correlate with human %F. Machine learning...