Author

Madawa W Jayawardana

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Open access Aug 2026

Using Polygenic Risk Scores to Refine Risk and Outcomes in High-grade Serous Ovarian Cancer in Australia

It is shown that PRSs are unlikely to serve as therapeutic biomarkers but support their use for enhanced risk-stratified prevention and incorporation into clinical models may improve risk stratification and support targeted prevention.

Rachel Delahunty, S. M. Silva, A. Pandey et al. · Cancer Epidemiology, Biomark... · 0 citations

Open access Aug 2026

Spatial Profiling Reveals Immune Escape Pathways and Therapeutic Vulnerabilities in Prostate Cancer Bone Metastases.

Bone metastases showed marked suppression of tumor-intrinsic type I interferon (IFN-I) signaling and loss of antigen presentation, features that were strongly associated with reduced bone metastasis-free survival and could inform precision therapeutic strategies for PCa.

Katie L. Owen, L. Gearing, B. Niranjan et al. · Cancer Research · 0 citations