Sep 2026
Abstract C017: Patient-Derived iPSC Liver Organoids Model Embryonal Hepatic Reprogramming and Collagen IV-Integrin Signaling in BWS-Associated Hepatoblastoma
Beckwith-Wiedemann syndrome (BWS) is a cancer predisposition disorder caused by epigenetic alterations at chromosome 11p15, which confers increased risk of hepatoblastoma in early childhood. The mechanisms linking 11p15 dysregulation to tumor initiation remain unclear. Building on our previously published single-...
Snehal Nirgude, Madison Newsome, Elisia D. Tichy et al.
· Cancer Research · 0 citations