A hypoxia-responsive theranostic mesoporous silica nanoparticles for the selective delivery of PTX and a coumarin fluorescent dye to hypoxic tumors selectively reduced the viability of A549 lung cancer cells under hypoxic conditions while exhibiting high biocompatibility with healthy THP-1 macrophages in normoxia.
Paula Rodrigo-Martínez, Lamiaa Mohamed Ahmed Ali, C. Coll et al.· International journal of pha...· 0 citations
Although promising preclinical results highlight improved tumor control and antitumor responses, challenges related to safety, biodistribution, and clinical translation remain, challenges related to safety, biodistribution, and clinical translation remain are discussed.
Emilie Lambert, Christophe Nguyen, Sean E. Dunn et al.· Advancement of science· 0 citations
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