Sep 2026
Abstract B086: Mesothelin-targeted CAR Th1/17 cells are a novel cellular engineering platform for pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) remains refractory to immunotherapies, including adoptive T cell therapy, necessitating evaluation of alternative T cell engineering platforms in immunosuppressive solid tumors. Human CD4+ T cells co-secreting IFN-γ and IL-17A (Th1/17 hybrids) have demonstrated enhanced ant...
Delaney K. Geitgey, Megan M. Wyatt, Maggie J. Phillips et al.
· Cancer Research · 0 citations