Stimuli-Responsive Mesoporous Silica Nanoparticles for Precision Cancer Therapy: Design Principles, Cellular Uptake, and Translational Perspectives.
Premature drug release in the systemic circulation or at off-target sites remains a major challenge in conventional drug delivery systems, often resulting in reduced therapeutic efficacy and increased systemic toxicity. Nanotechnology-based delivery platforms have emerged as promising strategies to address these limita...