Author

Mahmoud A. Al-Sha'er

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Review Open access Sep 2026

Recent medicinal chemistry efforts of targeting protein kinases for treating neurological conditions of Parkinson's and Alzheimer's diseases

The human genome encodes a wide variety of protein kinases that regulate multiple cellular functions. These enzymes play a crucial role in amplifying and propagating intracellular signals during signal transduction. Dysregulation of protein kinase signaling is associated with vascular diseases, inflammatory disorders,...

Rajwinder Kaur, D. K. Lang, Ankita Sood et al. · RSC Advances · 0 citations

Sep 2026

Synthesis of Novel Benzoxazole–Piperazine Hybrids as Anticancer Leads: Biological, Molecular Docking, and ADMET Evaluations

The synthesized benzoxazole hybrid compounds showed promising anticancer activity with acceptable ADMET properties; however, further structural optimization and mechanistic studies are needed to validate the molecular targets and improve safety and pharmacokinetic profiles.

Mahmoud A. Al-Sha'er, A. H. Abdullah, Almeqdad Y. Habashneh et al. · Chemistry Africa · 0 citations