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Author

Mahmoud Abdelnaser

2 papers indexed here

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Review Aug 2026

Deciphering Gentamicin-Induced Nephrotoxicity and Hepatotoxicity: Pathophysiological Insights and Emerging Protective Approaches.

Gentamicin (GEN) is a critical aminoglycoside antibiotic for severe gram-negative infections, yet its clinical utility is limited by dose-dependent nephrotoxicity (occurring in 10-25% of therapeutic courses) and hepatotoxicity. Nephrotoxicity arises from GEN accumulation in proximal tubular cells, triggering reactive o...

Ehab E. Sharata, Reham H. Mohyeldin, Mahmoud Abdelnaser et al. · 1 citation

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