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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Mahmoud Moradi

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3 papers indexed here

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Open access Aug 2026

Dimer opening enables brain-type creatine kinase to sense membrane curvature

Brain-type creatine kinase (CK-BB) buffers local ATP demand through reversible phosphotransfer between ATP and phosphocreatine, yet how this soluble metabolic enzyme engages membrane compartments is unknown. Here, we combine fluorescence microscopy, DEER spectroscopy, hydrogen–deuterium exchange and native mass spectro...

Samantha Gies, Nolan K. McLaughlin, O. Kou et al. · 0 citations
Open access Jul 2026

Interplay Between Cholesterol Concentration and Membrane Curvature in Liposomes Revealed by Molecular Dynamics Simulations

Liposomes are widely used as model membranes and nanoscale drug delivery systems, where cholesterol plays a key role in regulating bilayer structure and dynamics. However, how cholesterol concentration influences the structure and dynamics of liposome and how this influence is dependent on membrane curvature are not fu...

E. Khodadadi, Mortaza Derakhshani-Molayousefi, E. Khodadadi et al. · 1 citation
Open access Aug 2026

Cholesterol-Dependent Structure and Dynamics of Curved Lipid Vesicles Revealed by Dry MARTINI Simulations

Cholesterol is a key regulator of membrane structure and dynamics, yet its effects on large curved vesicles under implicit-solvent coarse-grained conditions remain incompletely understood. Equilibrating large Dry MARTINI vesicles is challenging because transient membrane deformations can arise during the early stages o...

E. Khodadadi, E. Khodadadi, Mahmoud Moradi · 0 citations

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