Interpretable Prediction Of SARS-CoV-2 Drug Efficacy And Cytotoxicity Using Multivariate Adaptive Regression Splines
Accurate prediction of drug efficacy and cytotoxicity for SARS-CoV-2 is a critical step in early-stage drug development, guiding compound prioritization and identifying potential therapies. Ensemble-based algorithms such as Random Forest have demonstrated strong predictive performance in this domain; however, their rel...