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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Mahsa Fatahichegeni

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Review Oct 2026

Beyond the binding site: PROTAC-mediated protein degradation assists the therapeutic paradigm of hematological malignancies.

Hematological malignancies represent a growing global health burden, with conventional therapies limited by systemic toxicity and resistance mechanisms. Proteolysis-targeting chimeras (PROTACs) are heterobifunctional molecules that hijack cellular degradation machinery to eliminate, rather than merely inhibit, target p...

Mahsa Fatahichegeni, Mohammad Amin Ansarian, Yu-Qi Wang et al. · 0 citations

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