Mechanistic Origins of Chemoselectivity in Trifluorodiazoethane [3 + 2] Cycloadditions: Pseudoradical Versus Zwitterionic Reactivity
The competition between the three-component synthesis of spiro-oxazolidine oxindoles and the two-component formation of spiro-cyclopropane-oxindoles from trifluorodiazoethane, nitrosoarenes, and phenacylideneoxindoles was investigated within the molecular electron density theory (MEDT) at the M06–2X/6–311G(d,p) compu...