The actin cytoskeleton generates diverse cellular functions, including intracellular positioning, symmetry breaking, and cell migration, through dynamic self-organization. Despite extensive molecular characterization of actin-binding proteins, the physical principles by which local molecular interactions give rise to c...
Makito Miyazaki· Biophysics and Physicobiolog...· 0 citations
The actin cortex, a thin layer of actomyosin network beneath the plasma membrane, regulates various cell functions by generating active forces and inducing membrane deformations, including blebs. Although upstream signaling is involved in regulating cell shape, the extent to which downstream actomyosin molecules can co...
Makito Miyazaki, F. S. Laboni, Taeyoon Kim· Science Advances· 0 citations
These results indicate expansion in microtubule protofilament number during eukaryogenesis, and suggest microtubule-like polymers can form from a range of protofilament numbers, with reduced architectures potentially adapted to small cellular dimensions and lower mechanical loads.
L. Tran, Samson Ali, Tomoharu Matsumoto et al.· Science Advances· 0 citations
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