Open access
Sep 2026
β4-integrins safeguard nuclear mechanics to suppress prostate cancer progression
Prostate cancer (PCa) progression is accompanied by profound alterations in cell-extracellular matrix (ECM) adhesion, nuclear architecture and mechanical adaptability, yet the molecular mechanisms linking these processes remain poorly understood. Hemidesmosomes (HDs), formed by α6β4-integrins, anchor epithelial cells t...
Anette Schmidt, Rong Wei, Paulina Nastały et al.
· bioRxiv · 0 citations