Cancer nanotechnology: a new approach to upgrade cancer diagnosis and therapy
Dorsa Morshedi, Hojjatollah Nazari, V. Y. Naei et al.
· 3 citations
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2026
Allele-specific disruption of KRAS p.G12V in colorectal cancer cells using electroporated Cas9 RNPs
Objective(s): Colorectal cancer (CRC) is a major cause of mortality, and KRAS mutations drive tumorigenesis and therapy resistance. Although CRISPR-Cas9 enables precise genome editing, intracellular delivery of Cas9 ribonucleoproteins (RNPs) remains challenging. We evaluated direct electroporation of Cas9-sgRNA RNPs ta...
Firouzeh Morshedzadeh, Samaneh Sharif, M. Peymani et al.
· Iranian Journal of Basic Med... · 0 citations