Author

Man-Kit Lei

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Open access Sep 2026

Two Separable Aging Domains in Blood DNA Methylation Scores Developed for Cancer Research: Mitotic Replication and Early-Life Systemic Dysregulation

These findings suggest that blood-based DNAm aging measures do not reflect a single aging process but distinguish at least two cancer-relevant methylation domains: one reflecting replication-driven mitotic aging and hematopoietic cell-turnover biology, and another reflecting early-life systemic dysregulation vulnerabil...

Katelyn N. Austin, Man-Kit Lei · Genes · 0 citations

Sep 2026

Mastery moderates the association between cumulative socioeconomic status risk and accelerated biological aging among middle-aged Black American women.

OBJECTIVES This study examines how exposure to cumulative socioeconomic status (SES) risk in midlife shapes subsequent biological aging among Black American women and tests whether a sense of mastery moderates these associations. METHODS Using longitudinal data from 334 middle-aged Black American women in the Family...

R. Weaver, Katelyn N. Austin, Man-Kit Lei · The journals of gerontology.... · 0 citations