Early-life adversity and abnormal myelination are implicated in psychiatric disorders, but how developmental myelination influences adult social cognition remains unclear. Here, we tested whether disrupting developmental myelination in the medial prefrontal cortex (mPFC) impairs adult social behavior. Using complementa...
Introduction Assessment of autism spectrum disorder (ASD) relies on both parent-reported questionnaires and clinician-administered observational instruments. Although discrepancies between informants are common, their implications for autism severity evaluation remain unclear. This study examined informant discrepancie...
Rio Ishida, Kazuhiko Yamamuro, N. Kashida et al.· Frontiers in Psychiatry· 0 citations
Autistic traits are commonly assessed using self-reported questionnaires, informant-reported measures, and clinician-administered diagnostic instruments; however, the convergence among these approaches and how they vary according to sex remain incompletely understood. We aimed to examine associations and discrepancies...
Rio Ishida, Kazuhiko Yamamuro, N. Kashida et al.· Autism Research· 0 citations
Background Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by social communication differences and restricted, repetitive behaviors. Convergent evidence implicates prefrontal cortex (PFC) circuit dysregulation and chronic neuroimmune activation in ASD. Despite increasing off-label use of...
The preliminary and exploratory findings tentatively suggest that microstructural variability in the temporal cortex and OFC may relate to auditory neural responses and to sensory and cognitive features of ASD, but these results should be regarded as hypothesis-generating rather than confirmatory.
N. Kashida, Kazuhiko Yamamuro, K. Matsuoka et al.· Frontiers in Psychiatry· 0 citations
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