Manjunath P. Pai

Vancomycin Population Pharmacokinetics and Exposure Variability in Children with Multiple Organ Dysfunction Syndrome.

In children with multiple organ dysfunction syndrome (MODS), vancomycin dosing is frequently guided by population-based approaches followed by therapeutic drug monitoring that requires considerable blood volumes. We sought to develop a population pharmacokinetic (PK) model and describe vancomycin exposures using blood-...