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Manu Sharma

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#diffusion models Open access Oct 2026

An Engineered Floating Nanoparticulate System to Modulate Biopharmaceutical Performance and Therapeutic Efficacy of Tapentadol in Chronic Neuropathic Pain Management

Background: Tapentadol is an effective centrally acting analgesic for treating neuropathic pain. However, its short half-life, high first-pass metabolism, and requirement for frequent dosing limit its therapeutic effect and patient compliance. The purpose of the present innovation was to develop cost-effective tapentad...

Ranju Soni, Sheelu Sharma, Manu Sharma · 0 citations

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