Subacute thyroiditis (SAT) is a self-limited inflammatory thyroid disorder that typically produces a transient thyrotoxic phase. Intracranial hypertension (IH) is a rare but potentially sight-threatening complication of thyrotoxicosis, reported almost exclusively in hyperthyroidism, with only a single previous report l...
Mariapia Griffo, Chiara Muzio, Elisabetta Bernardi et al.· Frontiers in Neurology· 0 citations
Background Frailty is characterized by declining homeostatic reserves and increased vulnerability to stressors, and has been associated with cognitive decline and dementia. Objective To examine the relationship between frailty, Alzheimer's disease (AD) biomarkers, and cognitive performance in individuals with mild cogn...
Manuela Pintus, M. Valletta, L. Sacchi et al.· Journal of Alzheimer's Disea...· 0 citations
Factor analysis indicated that DTI-ALPS clustered with MA and ODI rather than forming a distinct factor, suggesting that DTI-ALPS primarily reflects WM diffusion dispersion and heterogeneity rather than glymphatic flow in the context of neurodegeneration.
L. Sacchi, Giovanni Farruggio, Giorgio Bocca et al.· bioRxiv· 1 citation
CP enlargement is associated with reduced DTI-ALPS and greater WML burden, but the contribution of glymphatic impairment remains uncertain, and alternative mechanisms may contribute to these findings.
L. Sacchi, Valentina Veronesi, Giorgio Bocca et al.· Journal of Alzheimer's Disea...· 0 citations
Findings support the presence of a compartment-specific reorganization of inflammatory signalling during AD progression and highlight the potential of MDEVs as accessible peripheral biomarkers of neuroinflammatory processes in AD.
Chiara Bianchessi, M. Serpente, E. Ferri et al.· GeroScience· 0 citations
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