Review
Open access
Oct 2026
Impact of Aggregation on the Immunogenicity of Therapeutic Recombinant Biological Products
Background: Therapeutic recombinant biological products are essential in modern medicine, but their immunogenicity remains a major concern for both clinical safety and therapeutic efficacy. Protein aggregation may occur during manufacturing, storage, transportation, and administration, potentially increasing immune rec...
Xiao-Ying Chen, Sha Guo, Xiao-Rui Feng et al.
· Pharmaceuticals · 0 citations