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Open access Aug 2026

Frailty, social disconnection, metabolomic signatures, and incident peripheral artery disease in type 2 diabetes: a prospective cohort study

Frailty, loneliness, and social isolation remained associated with incident PAD after mutual adjustment among individuals with T2DM, and the potential relevance of physical vulnerability and social disconnection to PAD risk is supported, while the metabolomic findings require external validation.

Li Zhao, Xin-Rui Xue, Tian-Jiao Li et al. · 0 citations

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