Muscle-invasive bladder cancer (MIBC) exhibits significant heterogeneity in clinical outcomes and treatment responses. While gene expression profiling has provided important biological and prognostic insight, transcriptomic assays are not routinely incorporated into standard clinical practice, in part due to cost. AI m...
I. F. Mathisen, F. Koll, R. Mayer et al.· Modern Pathology· 0 citations
AtlasLens is developed, an open-source R/Shiny application for interactive exploration of scRNA-seq datasets and integrated cellular atlases that integrates interactive visualization, differential expression analysis, Gene Ontology enrichment with redundancy reduction, temporal expression analysis, and context-dependen...
Shamim Ashrafiyan, Iaroslav Kosaretskii, Marcel H. Schulz· bioRxiv· 0 citations
This work provides a foundation for applications that link epigenome variation to gene expression in human cells, by benchmarking methods on a per-gene basis, illustrating their use in a disease context and making trained models available to the community.
Fatemeh Behjati Ardakani, Shamim Ashrafiyan, Laura Rumpf et al.· Genome Biology· 0 citations
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