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Author

Marcela Briones-Martin-Del-Campo

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Open access Aug 2026

SNHG family lncRNAs promote Ewing sarcoma cell fitness through intronic snoRNA-guided rRNA modifications

Abstract Over 90% of Ewing sarcomas (EWS) are driven by the EWS–FLI1 fusion oncoprotein. EWS–FLI1 acts as a pioneer transcription factor, altering the expression of hundreds of genes including many long non-coding RNAs (lncRNAs). The role of these lncRNAs in the oncogenesis of EWS is mostly unknown. We developed a CRIS...

Marcela Briones-Martin-Del-Campo, Alex G. Lee, Truc Dinh et al. · 0 citations

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