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Author

Marcello Iriti

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Open access Oct 2026

3,4-Dimethoxyacetophenone ameliorates epileptogenesis by suppressing BDNF, c-fos, and JAK-2/ STAT-3 expression in a pentylenetetrazole-induced kindling model of epilepsy.

Epilepsy is a neurological condition that affects approximately 50 million individuals worldwide. Current treatments mainly alleviate symptoms and have substantial adverse effects, with about 1/3 of patients not responding to existing medications. This underscores the urgent need for new drugs that can overcome these c...

S. Ali, Muhammad Jamal, M. Ayub et al. · 0 citations
Review Open access Sep 2026

Phytochemical-mediated targeting of signaling pathways in glioblastoma: preclinical evidence, translational potential, and emerging nano-based therapeutic approaches.

Overall, phytochemical modulation of signaling pathways paired with nano-based drug delivery shows potential for enhancing treatment efficacy in GBM.

Md. Rezaul Islam, Abdur Rauf, Hanan A. Ogaly et al. · 0 citations
Review Open access Aug 2026

Phytochemicals as Multitarget Therapeutics in Pancreatic Cancer: Mechanisms, Clinical Evidence, and Translational Challenges

This review demonstrates the therapeutic potential of phytochemicals as multitarget agents in pancreatic cancer, emphasizing their molecular mechanisms, pharmacological properties, and translational relevance.

Md. Rezaul Islam, Abdur Rauf, F. Shourav et al. · 0 citations

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