Open access
Aug 2026
Molecular Basis for Activation to Inhibition Switching in Kv7.2 Channel Modulators.
Kv7 voltage-gated potassium channels play a critical role in controlling electrical properties of excitable tissues. Neuronally-expressed Kv7 channels are involved in both common and rare neuropsychiatric disorders, ranging from epilepsy to depression and neurodegenerative diseases; thus, they represent attractive ther...
T. Ciaglia, G. Carleo, Zhenni Yang et al.
· Angewandte Chemie · 0 citations