Sep 2026
An integrated genome-wide resource reveals distinct replication environments of DNA breakage in human cancer cell lines
An integrated genome-wide resource of DSBs, DNA replication, replication timing, transcription, and R-loops in two widely used cancer cell lines, under steady-state conditions and following prolonged low-dose DNA polymerase inhibition is established.
Bo-Yu Ding, Alex Ing, Li-Chin Wang et al.
· bioRxiv · 0 citations