Sep 2026
A noncontiguous code for RNA-guided DNA recognition at the origin of CRISPR-Cas.
Peter H. Yoon, Kenneth J. Loi, Zeyuan Terry Zhang et al.
· Science · 0 citations
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Aug 2026
Reprogramming Cas9 PAM Recognition for Allele-Specific Editing
A yeast selection platform is developed to engineer Cas9 with re-specified activity across multiple additional non-canonical PAMs in yeast, further demonstrating its utility as a general and programmable framework for expanding the therapeutic reach of precision genome editing.
Julia Tartaglia, Vivian Nguyen, John James Desmarais et al.
· bioRxiv · 0 citations