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Author

Margi Patel

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Open access Sep 2026

Impact of Renal Iron Overload on Sickle Cell Nephropathy in a Humanized Mouse Model.

Increased morbidity and mortality are associated with iron overload in sickle cell disease (SCD). Renal iron accumulation, a direct consequence of intravascular hemolysis, occurs in both patients and murine model of SCD, and correlates with albuminuria, an early marker of kidney injury. We aimed to investigate the role...

Mohammad O. Sako, Bryant J. Kane, Michael Booze et al. · 0 citations

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