Open access
Aug 2026
EP259 - ECE_2188 - CD4+ T cells senescence decreases bone density by changes in genes related to calcium and phosphorus homeostasis
Mice with senescent CD4+ T cells displayed reduced bone mineral density and impaired structural integrity, likely due to enhanced osteoclastic activity at the expense of osteoblast function, combined with diminished responsiveness to hormonal regulation resulting from decreased receptor expression.
Daniel Cabello-Rivera, Rosa Plaza-Clavero, Luna Ballesteros-Arias et al.
· European Journal of Endocrin... · 0 citations