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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

Maria Dimitriadi

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2 papers indexed here

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Open access Sep 2026

Treating Smn2B/− spinal muscular atrophy (SMA) mice with commercially approved metabolism-targeting interventions leads to improved disease phenotypes

Spinal muscular atrophy (SMA) is an autosomal recessive neuromuscular condition that is increasingly recognized as a multi-systemic disorder in which metabolic dysfunction plays a central role. Reframing SMA pathology from a neurocentric to a metabolic perspective reveals abnormalities in metabolic tissues such as...

Özge Çetin, E. McCallion, Joseph M. Hoolachan et al. · 0 citations
Open access Sep 2026

Pharmacological Activation of Autophagy Ameliorates Neuromuscular-Associated Defects and Extends Lifespan in a Caenorhabditis elegans Model of Spinal Muscular Atrophy

Findings support enhancing autophagic activity as a combinatorial treatment strategy for SMA patients by identifying that pharmacological activation of autophagy, but not inhibition, significantly improved neuromuscular function, as indicated by two independent functional readouts.

Saman Rashid, Coral Crespo Gómez, Maria Dimitriadi · 0 citations

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