Jul 2026
Stimulating the resolution of inflammation overcomes CD8+ T cell exhaustion and boosts immunotherapy 2255409
RvD5 reduced PD-1 expression on T cells and PD-L1 expression on cancer cells, thereby restoring T cell antitumor functions by delaying their differentiation into Tex, and suppresses tumor growth by dampening inflammation and delaying T cell exhaustion within the TME.
Maria Tredicine, Simona D'Orazio, Nunzia Coletta et al.
· Journal of Immunology · 0 citations