Maria-Tsampika Manoli

Functional redundancy driven by isocitrate dehydrogenase enhances metabolic robustness in Pseudomonas putida KT2440.

Findings support a model in which specialized isoenzymes with conditional redundancy, rather than simple redundancy, in P. putida enables the cell to balance energy production with biosynthetic demands, which might facilitate metabolic adaptation under fluctuating environmental conditions.